A
retrospective study of 51 oral cancer patients at the Jordan University
Hospital
(1984
- 1998)
Burgan SZ, EL
Maaytah M, AL Masad JK, Farah GR, AL Zaben J
Cairo Dental Journal, vol 18
(1): 9-13, 2002.
ABSTRACT
This retrospective
study was conducted to determine diagnosis, treatment and
survival of 51 consecutive patients with oral squamous cell
carcinomas treated at the Jordan University Hospital between
1984 and 1998. Male patients predominated (84%), with a mean age
of 63.4 years. Seventy one percent were current smokers, and 12%
drank alcohol. Most patients (84%) were symptomatic at
presentation and the tongue was more frequently involved. Many
(71%) presented with stage III-IV tumors, and 63% had lymph node
metastases. Nodal involvement increased significantly from 40%
in T1 to 82% in T2. Floor of the mouth lesions had the worst
prognosis. The overall 2-year survival rate was 47%, which fell
with increasing stage from 80% (I-II) to 33% (III-IV), and with
the progression of tumour size from 73% (T1) to 9% (T4).
Patients presented with no evidence of nodal disease had better
survival (74%) than those with nodal disease (31%). Survival
also fell from 59% in grade I-II to 8% in grade III-IV. Patients
treated with surgery (54%) or with postoperative radiotherapy
(50%) had better survival than those treated only with
radiotherapy (20%). It is concluded that tumor site, size,
differentiation and nodal disease were significant predictors of
survival. |
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